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tained about an ounce of the tincture of opium! (thirty grammes.) The man swallowed it, and died in three quarters of an hour, violently convulsed. The minister of war ordered an investigation of the circumstances.
M. Fretin, the accused, was interrogated on the allegation of his having labelled a bottle, containing tincture of opium, “sudorific syrup,” but he denied that he had made any mistake, and contended that he was not responsible for the result. The accused was defended by counsel, and the court, after hearing the defence, acquitted him of the charge.—Journul de Medecine..
*** The case is chieffy remarkable from the fact that it is perhaps the most rapid instance of poisoning by opium on record. --- London Med. Gaz.
French Medical Students.-By a decree just issued from the University of France, it has been ordered that, after the 1st of November, 1846, all medical students shall undergo an examination at the end of each of the three years of study. In the first year, on physic, chemistry, and natural history; in the second year, on anatomy and physiology; and in the third year, on pathology. There will be three examiners, and four students at each examination. The examinations will take place between the 15th of July and the 1st of August, and any student who fails to satisfy his examiners, cannot again present himself until the following November. Unless he then passes, his ticket for the ensuing quarter will be withdrawn. If again rejected in November, he must resume his studies for a year.
These rules are severe, but they embody a much better method of testing the knowledge of a candidate than the mere forms of examination which are gone through in this country, upon all kinds of subjects, at one sitting of an hour's duration.-Med. Gaz.
Phosphorescence of the Human Body. The subject of this case was a male infant sixteen months old. The child had suffered from teething, and had been casually seen by Dr. H. M'Cormack, of Bela fast. An emetic was administered, and an irritating liniment rubbed on the breast. The nurse, in raising the child in bed at night, obsreved a phosphorescent light about the hips, both before and after the candle had been lighted. The legs were also observed to be luminous for a short time. From what Dr. M'Cormack could learn, the appearances very much resembled that produced by phosphora ized oil, but none of this had been employed. The phenomenon occurred only once. The mother had, however, observed, that on one occasion a spark (electrical), had flown to her hand from the infant's body. Cases of human phosphorescence in the living body are rare, and the fact recorded by Dr. M'Cormack is, therefore, interesting.-- 1b.
Rape on an Idiot. Reg. v. Ryan.-The prisoner was indicted for rape. The prosecutrix was an idiot, and when asked questions in the witness.box was evidently unconscious of their purport, and not in a condition to understand right from wrong. Plait, B., interrogated her father as to her general habits, whether they were those of decency and propriety, and an answer in the affirmative was returned.
Platt, B. in summing up. The question is, did the connection take place with her consent ? It seems that she was in a condition incapable of judging, and it is important to consider whether a young person, in such a state of incapacity, was likely to consent to the embraces of this man; because if her habits, however irresponsible she might be, were loose and indecent, there might be a probability of such consent being given, and a jury might not think it safe to conclude that she was not a willing pariy. But here the presumption is that the young woman would not have consented; and if she was in a state of unconsciousness at the time the connection took place, whether it was produced by any act of the prisoner, or by any act of her own, any one having connexion with her would be guilty of
rape. If you believe that she was in a state of unconsciousness, the law assumes that the connection took place without her consent, and the prisoner is guilty of the crime charged. The prisoner was convicted. -Ib. from Law Times.
Delirium Tremens in an Infant.— A litile boy, five years of age, swallowed by mistake a large quantity of brandy. Vomiting speedily followed, and he passed a restless night, sleeping only towards morning. On awaking, it was observed that he had iremor of the hands, and that he could not hold a cup steadily. Convulsions with cramps ensued. The pulse was slow, the look timid, the pupils dilated, and the countenance pale. Dilirium supervened, and there was dysuria with great thirst. A cataplasm was applied to the abdomen, and calomel and jalap were administered. The symptoms abated about the middle of the day ; but towards evening there was a return of the tremors with other nervous symptoms. An opiate was exhibited, from the effects of which the child slept soundly, and on awaking the whole of the symptoms had disappeared.—Guz. des Hóp.
A novel method of detecting a necille by means of Magnetism, and its extraction. By R. T. Gill, of New York.--On Friday, Novem. ber 13th, 1846, Miss D., while kneeling upon the carpet run a cambric needle into her knee, and broke it. The usual ineffectual search having been made, it occurred to me, that a magnetic needle would deteci it, and if the needle could be charged, its poles might be located. For this purpose, the north pole of a horse-shoe magnet was drawn several times from above downwards, over the point of entrance. Then having charged a darning needle, suspended by means of a thread, and holding it near the point where the cambric needle had entered, it was found to have slight polarity.
The horse-shoe magnet was then bound below the knee, diagonally
across, so as to present the north pole towards the point of entrance, that the needle might thus be charged more effectually by induction. On the 16th, a proper magnetic needle having been procured, and presented to the knee, its north pole was strongly attracted to a certain point, which was marked with ink ; then on presenting the south pole, and moving it up about three-quarters of an inch, it was strongly attracted, and that point also marked. An incision at right angles, bisecting the disc between the two marks, struck the needle at ils centre. Having passed a curved needle under it, so as to fix it, ihen cutting down upon one of its points, it was extracted.
The needle had moved more than its length below the place of entrance, caused somewhat, possibly, by the attraction of the horse. shoe magnet.-N. Y. Annalist.
Upon the Eficacy and Mode of Administration of Belladonna and Atropia. By W. R. Wilde, M. R. I. A., Surgeon to St. Mark's Ophthalmic Hospital. One of the greatest improvements in the oculist's materia medica of late years has been the introduction of the alkaloid denominated Atropia, which, we believe, we were the first io introduce into practice in this city, upwards of two years ago. It was procured for is by Messrs. Bewley and Evans, who have solutions of it according 10 our formulæ, of the following strengths : one grain, two grains, and three grains to one drachm of distilled water, and three drops of spirits of wine, and numbered 1, 2, and 3. The salt is rendered soluble by the addition of a drop of dilute nitric acid, and the spirit is added to make the solution keep.
A single drop of number 1 placed upon the conjunctiva of the lower lid (where it causes neither pain nor irritation,) in a healthy eye, dilated the pupil, in a period of time varying from five to fisteen minutes, 10 double, or even inore than the ordinary medium size, and will retain it so, upon the average, from four to five days; at which period it generally begins to contracı, but the pupil does not sully regain its previous size, nor the iris its mobiliiy, till the sixth or seventh day. There will be, no doubi, exceptions to this rule, particularly in cases where there may be such an idiosyncrasy present as would render the eye susceptible to the action of the atropa belladonna used in any form, and perhaps keep the pupil permanenıly dilated for months. To counteract ihis effect of the solution number 1, we have employed upon the second and third day after its application those remedies which generally excite the pupil to contract, such as sudden exposure to strong light, the application of electro-magnetism, the use of opium, and the application of the vinous tincture of that medicine upon the conjunctiva ; but each and all these means failed to lessen the size of the pupil, in many instances, until the end of the third, or fourth, or fifth days. Solutions number 2 and 3 produce a more decided effect upon the iris, and in a shorter space of time, and retain the pupil dilated for a longer period-even to the eighth or tenth day. When the object is to keep the pupil in a state of permanent dilalation, as in cases of iritis and aquo-capsulitis, as well as to try and break up recent adhesions between the iris and lens, or to withdraw the iris
from protruding through an aperture caused by a wound or ulcer near the centre of the cornea ; in all cases of central cataract; where the cornea is opaque in its central portion, or that a portion of the pupillary margin of the iris is attached to the back of the cornea, after the dislission of a cataract; or, in fact, in any case in which we wish to produce permavent or complete dilatation of the iris, the solution of atropia will be found much more efficacious than the usual mode of applying the extract of belladonna externally. It is, moreover, much more cleanly, and.is not liable to the objection urged against the latter, of producing an unpleasant eruption around the brow on which it is applied, and it is preferable to the ordinary mode of placing a few drops of the solution of the extract between the palpebræ, inasmuch as it causes no pain nor irritation.
In cases, however, where there is much conjunctivitis, or even deeper seated infammation, attended with lachrymation, present, it does not possess the immediate and marked power over the iris which it does in ihe healthy eye, and its effects pass off much sooner; and this remark is applicable even to the three-grain solution. It is possible that in such cases the mucous discharge, and particularly the lachrymation which is present, may dilute it too much, or the morbid irritability and increased vascularity of the organ may render it less susceptible of the local application of this remedy than it would be in an otherwise healthy condition, therefore, in cases of violent irritic inflammation, the syphilitic for inslance, where the disease had considerably advanced, and extensive exudations of lymph had taken place, we would not solely depend upon the atropia solution, but likewise apply the extract round ihe orbit. In cases of recent protrusion of the iris through the central portion of the cornea, the result either of injury, or rupture from ulceration, &c., and when there was no great irritability and blepharospasmus present, we have applied the strong atropia solution externally, by means of a small portion of linen rag wet with it, and retained for a short time upon the closed eyelids, with the most happy results.
We may here remark that the benefits arising from dilatation of the pupil have not been sufficiently attended to in the general treatment of olcers of the cornea. We have, on several occasions lately, been able not only to save the eye, but even to prevent adhesions between the cornea and iris (synechia anterior,) and consequent blemish, by means of the judicious application of the preparations of belladonna. In cases of rupture from ulceration, when we have seen the patient shorıly after the rupture occurred—and in many of those instances hernia of the iris had absolutely taken place—we at once applied the atropia solution, closed the lids, kept them in that condition with isinglass plaster, and then applied a large pledget of lint smeared with the extract of belladonna over the eye and brow, and retaineil it in position by a light handage, at the same time that we employed, when necessary, local depletion by means of lecches on the temples and over the malar bone, together with blistering, and constitutional treatment calculated 10 lower the inflammation and prevent the further spreading of the sloughy or ulcerative process in the cornea. We keep the eye covered up in this state for thirty-six or fortyeight hours, and have had, in most instances, the satisfaction of finding, VOL. X.
when we came to examine the eye, that the iris had been withdrawn from the wound, the pupil had dilaied, and the cornea had uvited.
There are, however, certain cases in which the use of atropia is inad. missible, namely, in examining the eye for cataract, where we do not wish the dilatation of the pupil to continue longer than a few hours, if possible. In cases where we wish to dilate the pupil before we perform the operation for absorption of the lens, we have more than once seen unpleasant consequences result after this manner. It is well known to operative ophthalmic surgeons, that after the dilatation with the ordinary belladonna extract or infusion, the iris will, during the operation of keratonyxis, partially contract, either from the loss of a few drops of aqueous humour, or from iis irritability being excited by the side or flat of the needle touching the margin of the pupil, or from the cataractous lens, whole or in a broken condition, pressing against it: and this condition is rather serviceable than otherwise, for should the lens be inclined to start from its bed, and press forward through the pupil into the anterior chain. ber, the iris acts as a partition to keep it in its place ; while in a few hours the aqueous fluid is regenerated, the iris falls back into its natural position, and can afterwards be kept dilated by the continued external application of the belladonna.
Is, however, the pupil has been previously dilated by the atropia, it is ihoroughly immoveable, and the lens is liable either to press into it or become dislocated, and get into the anterior chamber. This latter accident occurred to us some time since, in breaking up the lens for congenital cataract. We had ordered a solution (No. 2) of atropia to be dropped into the eye the night previously, and on arriving in the morning we found the iris reduced to a mere ring. The child struggled a good deal, and a few drops of the aqueous liquid were lost during the operation, which consisted in a mere crucial incision into the capsule. On withdrawing the needle we remarked that there was no contraction of the pupil, into which the lens pressed. On visiting the child in the evening ii had been so uneasy and complained so much of pain, and there was so much lachryination present, that we were induced to remove the bandage and examine the eye. The cornea was found 10 have become plump, from the regeneration of the aqueous fluid, but the iris had remained immoveable, and the lens had started into the anterior chamber, where it caused considerable irritation and subsequent inflammation. It absorbed completely, however, without a second operation, and in a much shorter time than usual.
In cases of photophobia following cataract and other operations on the eye, and attended with myosis, which had resisted the continued external application of belladonna, as well as the strong atropia solution dropped into the eye, we have found the most marked beneficial elfects result from the internal administration of the extract of belladonna, given in the form of solution, to the amount of the sixteenth of a grain, from three to five times a-day. This, in the course of thirty-six or forty-eight hours has seldom failed to relieve the pain and intolerance of light, and also to dilate the pupil as far as possible.
In neuralgic affections of the eye, characterized by pain of a burning