Genes, Environment, and Psychopathology: Understanding the Causes of Psychiatric and Substance Use DisordersGuilford Press, 01.11.2007 - 412 Seiten This groundbreaking volume synthesizes the results of the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders, which yielded longitudinal data on more than 9,000 individuals. The authors trace how risk for depression, anxiety, eating disorders, antisocial behavior, alcoholism, and substance abuse emerges from the interplay of a variety of genetic and environmental influences. Major questions addressed include whether risk is disorder-specific, how to distinguish between correlational and causal genetic and evironmental factors, sex differences in risk, and how risk and protective factors interact over time. The book also summarizes the conceptual underpinnings of the study and describes key methodological challenges and innovations. |
Inhalt
Introduction | 1 |
PART IBACKGROUND | 9 |
CHAPTER ONEThe Scientific and Social Context of the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders | 11 |
CHAPTER TWOMethodology Used in the VATSPSUD | 20 |
CHAPTER THREETwinning and Twin Models | 34 |
PART IIGENETIC RISK | 49 |
CHAPTER FOURInternalizing Disorders | 51 |
CHAPTER FIVEExternalizing and Substance Use Disorders | 81 |
CHAPTER ELEVENThe Genetics of What? | 199 |
CHAPTER TWELVEThree Extensions of the Twin Model | 229 |
PART VBRINGING IT ALL TOGETHER | 249 |
CHAPTER THIRTEENThe Genetics of the Environment | 251 |
CHAPTER FOURTEENMechanisms for Genetic Control of Exposure to the Environment | 267 |
CHAPTER FIFTEENIs the Relation between Environmental Risk Factors and Psychiatric Disorders Causal? | 275 |
CHAPTER SIXTEENGenetic Control of Sensitivity to the Environment | 291 |
CHAPTER SEVENTEENIntegrative Models | 320 |
CHAPTER SIXTwin Model Assumptions | 114 |
PART IIIENVIRONMENTAL RISK | 127 |
CHAPTER SEVENChildhood Experiences and Risk for Psychopathology | 129 |
CHAPTER EIGHTAdult Experiences and Risk for Psychopathology | 148 |
PART IVA CLOSER LOOK AT GENETIC AND ENVIRONMENTAL INFLUENCES | 167 |
CHAPTER NINESex Differences | 169 |
CHAPTER TENGenetic and Environmental Influences on Stability and Change | 181 |
CHAPTER EIGHTEENConclusions | 339 |
References | 351 |
Publications from the VATSPSUD | 377 |
391 | |
401 | |
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Häufige Begriffe und Wortgruppen
abuse abuse/dependence adolescence adult agoraphobia American Journal analyses anxiety disorder assessed association Behavior Genetics bulimia bulimia nervosa caffeine cannabis causal Chapter childhood comorbidity correlation cotwin criteria develop drinking drug DSM-III-R DZ pairs Eaves environmental factors environmental influences environmental risk factors epidemiological episodes etiology evidence female twins genes genetic and environmental genetic effects genetic factors genetic influences genetic risk factors hazard ratio Heath heritability history of MD illicit included increased risk individual-specific individuals interviews Journal of Psychiatry Kendler Kessler levels LTCT major depression measures MZ twins Neale neuroticism onset panic disorder parental loss predicted Prescott problems psychiatric and substance psychiatric disorders Psychological Medicine psychopathology reported risk for MD sample sex differences shared environment shared environmental effects Sidebar similar SLEs social phobia social support stressful life events substance use disorders symptoms trait twin method twin model twin pairs twin study variables variance VATSPSUD women zygosity
Verweise auf dieses Buch
Developmental Psychopathology and Wellness: Genetic and Environmental Influences James J. Hudziak Eingeschränkte Leseprobe - 2009 |