and may have been the effect of some change of constitution at that period, rather than of the lobelia. The remedy, however, is worthy of trial in this most common and most troublesome affection. Y.

SATURATED ALCOHOLIC TINCTURE ON EUPATORIUM PERFOLIATUM.

WHEN in Galliopolis, Ohio, we were informed by Dr. Hibbard, that he is in the habit of treating ague and fever with this tincture. He gives it in teaspoonful doses several times during the intermission. It is intensely bitter, and neither purges, vomits nor sweats the patient. He has not found the decoction to answer the same purpose. He administers a decoction of Aristolochia Sepentaria at the same time. The Doctor assured us, that he had found this treatment successful in a great number of cases; and it might, he thinks, be made to supercede in a great degree the use of the sulphate of Quinine.

D.

CONGENITAL FUNGUS HEMATODES.

THE first and only case of congenital fungus hæmatodes, or Encephaloid, we have ever seen, fell under our observation, in the vicinity of Athens, Ohio, in a late trip to that town. We were indebted to Drs. Carpenter and Blackstone for the opportunity of seeing it.

The child, a female, was two days old. The disease occupies the whole of the left nates, which is swelled out into a great, shining, globoid tumour; rendered irregular by tuberous elevations. It extends from the perineum, anus and vulva to the sacrum and the spine of the ilium, so as to involve the acetabulum. Its colour is deep red. Many of the cutaneous veins are much enlarged. A portion of the skin had suffered abrasion and considerable hæmorrhage had already occurred. Some parts of the tumour are hard, others soft the general mass felt hard. It was tender under the hand. In short it had all the diagnostic marks of encephaloid, before fungous growths appear. The child was rather lean but seemed to be in health; and was free from tumors or malformations in any other part. From this case it would appear, that this variety of carcinoma occurs throughout a much more extended period of life

than schirrhus, for we have seen it up to the 50th year. - - while the latter prevails most in advanced life, is perhaps never congenital and not often a complaint of youth.

D.

MILK-SICKNESS.

When lately at Urbana, Ohio, we collected from Dr. Carter, who has practised medicine in that town for more than a quarter of a century, the following facts, relative to the production of "MilkSickness," or "Sick-Stomach." Formerly the disease prevailed much more than within the last 8 or 10 years. This, Doctor C. ascribes to the confinement of cows within enclosed pastures. The neighborhood of Urbana presents, at the surface, two geological varieties: first, a true upland level, clayey, and covered chiefly with white oak, the soil thin, and reposing on a compact, arenaceous, ashgrey limestone: second, a diluvial formation, consisting in extensive, level deposites of rolled pebbles, gravel and sand, covered with black, carbonaceous mould, destititute of trees and clothed in long grass. Those tracts are evidently the beds of obsolete ponds and little lakes.

As long as cattle feed on the latter, according to the observation of Dr. Carter, the milk-sickness is not produced; when they frequent the woodlands, the disease is apt to occur. But it is not dangerous for them to feed in these natural pastures at all seasons of the year. Dr. Carter has never known them nor the people affected before the month of July, and, in most instances, not till August; from which till December is the time of greatest danger. He has never seen a case of the disease in man, that he could not trace up to the cow. Milch cows occasionally die, but on the whole are less liable than cattle which do not give milk. He knows of one tract of woodland three or four miles north-east of Urbana, which has been peculiarly fatal. Nearly all the following facts connect themselves with that spot.

Sixteen or eighteen years ago, a family living near it, had one milch cow, which was suffered to feed upon it. During the first August after their removal thither, and while they were using her milk, the father of the family sickened with the characteristic symptoms and died; and within a week from his death, the wife and two children, experienced the same fate, from attacks of the same kind

A young man living in the family had, at the same time, an attack of dysentery;-suggesting, undoubtedly, that the gastric disease which carried them off might have arisen from the same cause which produced his intestinal complaint. The cow was seized with the “trembles,” about the time the children were attacked, and died.

In the summer of 1837, in the month of August, the milch cows of Mr. Taylor, were suffered to range for a week in the same wood, during which they were milked as usual. The milk and butter made from it were eaten. A portion was also manufactured into cheese. Four of the family, two adults, and two children, all of whom had used the milk and butter, sickened with the well known symptoms, and one of the former died. The cheese was "thrown to the dogs" one ate of it and sickened; and some chickens which picked up fragments of it died.

In the month of October 1839, about twenty cattle escaping from their enclosures near this wood, were allowed to graze, or rather to browse, in it for 6 or 7 days, when several of them were found dead on the ground. The remainder were driven home, affected with the trembles. Some of them died the first night, and but one of the whole recovered.

Dr. Carter introduced us to Mr. Hitt, an intelligent and respectable farmer, who lives near Urbana, who informed us that he had lost many cattle by this malady; but has never seen it affect any which did not run at large, nor known it occur earlier in the calendar year than August. Two years ago in that month, his cattle ran abroad and one of the finest of them "got the trembles. He kept her from water, fed her on green corn (maize,) and drenched her with lard, as curative means. Finding that she did not improve in health, he determined to give her drink. After taking a few swallows of cold water, she fell down in convulsions, and to put an end to her sufferings he cut her throat. His two dogs ate of her carcase. In two days, one of them stiffened in his limbs "so that he could not jump over a low fence" and died. the other was affected with the same stiffening, but got well. His hogs, also, ate of the carcase, but were uninjured; but at another time, when he lost four cows, his hogs devoured a part of their carcases, and were destroyed.

We give these facts, with the observation that Dr. Carter is a regu、 larly educated physician, and an honest man.

D.

CASES OF PARTIAL PARALYSIS IN CHILDREN.

In the month of June when in Xenia, Ohio, Dr. Templeton afforded us an opportunity of seeing five children affected with partial paralysis. The resemblance to each other, of these cases, and the simultaneous occurrence of four of them, induced us to record the following particulars.

Case 1.-MR. SHEPPARD'S son, aged 15 months, generally enjoyed good health, and could walk very well, when a little more than a year old. About the middle of May, he became costive and fretful, and after a few days had decided fever. Three days after the supervention of the latter, palsy of the lower extremeties came on. It was perfect, that is to say, all power of the will over the muscles seemed to be gone, but the sensibility of the skin remained. The arms were unaffected, but the muscles of the trunk of the body were enfeebled, so that he could not sit up. The fever soon ceased. He took calomel and other cathartics. When we saw him, June 30, the right leg was nearly restored-the left remaining almost motionless. His general health appeared perfect. He had no spinal tenderness.

Case 2.-Mr. Moore's daughter, aged 20 months, was healthy from her birth, and walked when nine months old. In the latter part of May, she became costive, feverish, and was observed to have a weak and husky voice. She now and then screamed out in sleep, and at the end of a week had one spell of vomiting. Suddenly she lost the power of motion in her lower extremities, which for two days and nights were very cold. Their sensibility remained unimpaired. For three weeks, she could not even crawl nor stand; she then began to use the right limb moderately, and at the time we saw her, the left was moved in a slight degree, when the sole of the foot was tickled. An examination of the spine disclosed nothing. Before the paralysis supervened, a few drops of cathartic medicine were administered.

Case 3.-The son of Mr. Charters, 5 years old, was generally in good health, and properly developed both in body and mind, till about the middle of May last, when he was observed to be costive, and complained of headache and sick stomach. A cathartic was administered and he got better; but in a week he was again costive and feverish, with a dry husky cough. Cathartics were again exhibited

and were found to operate very tardily. In a few days it was observed, that when placed on his feet his legs were nearly paralysed, and he seemed to experience pain. Worm medicines, and calomel as a cathartic, were administered freely. No worms were discharged. In a few days he made efforts to walk, when assisted, but turned his toes outward, and dragged his feet. When we saw him, June 30, this debility and dragging still continued, but he was much better. It should be stated, that previously to the attack, his appetite was voracious and that he ate a great deal of meat.

Case 4.-A daughter of the same parents, aged 10 months, had been generally in good health up to the middle of May, when she became costive, irritable and feverish. The gums of the middle upper teeth, in front, being tumid and red, were cut. In a few days she partially lost the use of all her limbs, and the movements of her head were greatly weakened. Her voice was feeble and husky, and she had a short, dry, hoarse cough. The debility of her limbs increased; but in a day or two began to abate in all but the left leg and arm, which became nearly motionless. At the time of our examination, she had begun to move her limbs on that side a littlechiefly however by the flexor muscles, the extensors seeming to be entirely paralysed. Dr. Templeton could detect no spinal tenderness. She was treated with cathartic medicines, and was manifestly convalescent when we saw her.

Case 5.-Another, 3 years old, was shown to us, who in infancy was healthy, but when she began to use her hands and feet, it was observed that those of the left side were exceedingly inactive and feeble, compared with the others. When 20 months old, she began to walk, but still does it imperfectly-presenting her right side and dragging her left foot, with the toes turned a little out. Her fingers of the left hand are perpetually flexed. She often opens them with her right hand, so as to grasp what she would hold. She cannot protrude her tongue beyond her lower lip. The saliva drivels from her mouth, and in masticating, a portion of the food escapes from its corners, particularly the left, but she has no retraction of the right. She articulates very few words. Her mind is shrewd-her observations acute-her temper irritable-her communication with those around in a great degree pantomimic.

She was never subjected to any medical treatment. The mother