Privileged Chiral Ligands and CatalystsQi-Lin Zhou John Wiley & Sons, 10.02.2011 - 484 Seiten Catalytic asymmetric synthesis has been one of the most active research areas in chemistry (Nobel Prize in 2001). The development of efficient chiral catalysts plays a crucial role in asymmetric catalysis. Although many chiral ligands/catalysts have been developed in the past decades, the most efficient catalysts are derived from a few core structures, called "privileged chiral catalysts". This ultimate "must have" and long awaited reference for every chemist working in the field of asymmetric catalysis starts with the core structure of the catalysts, explaining why a certain ligand or catalyst is so successful. It describes in detail the history, the basic structural characteristics, and the applications of these "privileged catalysts". This novel presentation provides readers with a much deeper insight into the topic and makes it a must-have for organic chemists, catalytic chemists, chemists working with/on organometallics, chemists in industry, and libraries. From the contents: * BINAP * Bisphosphacycles - From DuPhos and BPE to a Diverse Set of Broadly Applied Ligands * Josiphos Ligands: From Discovery to Technical Applications * Chiral Spiro Ligands * Chiral Bisoxazoline Ligands * PHOX Ligands * Chiral Salen Complexes * BINOL * TADDOLate Ligands * Cinchona Alkaloids * Proline Derivatives |
Inhalt
| 1-8 | |
| 1-21 | |
Grignard Reagents | 1 |
Bisphosphacycles From DuPhos and BPE to | 21 |
Josiphos Ligands From Discovery to Technical | 2-43 |
Chiral Spiro Ligands | 50 |
Chiral Bisoxazoline Ligands | 11 |
PHOX Ligands | 5-59 |
Chiral Salen Complexes | 6-42 |
BINOL | 44 |
Asymmetric CC Bond Forming Reactions | 8-8 |
TADDOLate Ligands | 8-61 |
Deficient CC Double Bonds | 8-70 |
Cinchona Alkaloids | 8-100 |
| 16 | |
Andere Ausgaben - Alle anzeigen
Häufige Begriffe und Wortgruppen
active alcohols aldehydes aldol reaction alkenes alkyl allylic allylic substitution amines Angew aryl asymmetric catalysis asymmetric epoxidation asymmetric hydrogenation asymmetric reactions asymmetric synthesis bifunctional BINAP BINOL bisoxazoline ligands bond Brønsted carbon carbonyl compounds Catal catalyst catalytic asymmetric Chem chiral Lewis acid chiral ligands chiral spiro cinchona alkaloids complexes using chiral conjugate addition coworkers reported cyclic cycloadditions cyclopropanation Deng derivatives developed diastereoselectivity Diels–Alder reaction efficient electrophile enamine enantioselectivity Scheme enolate enones epoxidation esters ethyl excellent enantioselectivity Figure high enantioselectivity high yields highly imides imines intermediate intramolecular Jacobsen Jørgensen Josiphos Katsuki ketones kinetic resolution Lewis acid malonates Matsunaga metal center metal complexes metal-bisoxazoline metal/BINOL Noyori nucleophiles olefins organocatalysts oxide Pfaltz PHOX ligands racemic reactions catalyzed reactivity reagents ring ring-opening salen ligands Seebach Shibasaki Sibi silyl spiro ligands steric structure substrates Synlett Synth TADDOL Tetrahedron Lett Wang Yamamoto yields and enantioselectivities Zhang Zhou