Suicide Gene Therapy: Methods and Reviews

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Caroline J. Springer
Springer Science & Business Media, 2004 - 555 Seiten
The first comprehensive review of both the theory and practice of suicide gene therapy. The authors cover all the major aspects of suicide gene therapy, including the design and use of vectors in gene transduction, various enzyme and prodrug systems, the mechanistic analysis of the bystander effect, the design and synthesis of prodrugs, immunological implications, and its clinical impact. They also describe all the cutting-edge methods needed to explore, study, and advance understanding of the basic biology underlying gene therapy. Each fully tested method includes step-by-step instructions, a discussion of the principle behind the technique, equipment and reagent lists, tips on troubleshooting and avoiding pitfalls, and notes on the interpretation and use of results. Understand the latest developments in suicide gene therapy Use readily reproducible methods to explore, study, and advance suicide gene therapy Refer to the first book to integrate the theory and practice of suicide gene therapy.
 

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Inhalt

III
1
IV
29
V
46
VI
61
VII
71
VIII
91
IX
107
X
139
XVIII
331
XIX
345
XX
353
XXI
371
XXII
389
XXIII
403
XXIV
433
XXV
451

XI
161
XII
203
XIII
223
XIV
247
XV
263
XVI
279
XVII
303
XXVI
459
XXVII
479
XXVIII
491
XXIX
515
XXX
543
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